BWA Aligner Skill Purpose Enable BWA-MEM2 alignment for mapping sequencing reads to reference genomes with optimized parameter selection and quality assessment. Capabilities - Read alignment to reference genomes - Parameter optimization for different read types - Multi-threading configuration - Index generation and management - Alignment quality metrics reporting - Support for paired-end and single-end reads Usage Guidelines - Generate genome indices before alignment - Select appropriate parameters for read length and type - Use multi-threading for performance optimization - Validate alignmen…