pysam Overview Use pysam for low-level, streaming access to HTSlib-supported genomic formats: - and for SAM/BAM/CRAM - , , and for VCF/BCF - for indexed FASTA and for sequential FASTA/FASTQ - for BGZF-compressed, tabix-indexed BED/GFF/GTF/custom tables - and for wrapped command dispatchers Current upstream baseline: pysam 0.24.1 (7 September 2026), wrapping HTSlib/samtools/bcftools 1.24. Read before updating version-specific guidance. Installation Use the pinned release for reproducible work: Confirm the runtime: Prebuilt wheels are available for supported macOS and Linux platforms. A source…