Kepner-Tregoe Analysis Core rule: Diagnose deviations by testing causes against both IS and IS-NOT. Compare consequential choices by screening MUSTs, weighting WANTs, and exposing adverse consequences before selecting. When to Use - A defect affects some objects, places, times, or cohorts but not comparable others. - Several candidate causes remain and the contrast boundary can discriminate them. - A consequential option choice has explicit non-negotiables, competing objectives, and risks that should be compared consistently. When NOT to Use - A uniform failure has no meaningful IS-NOT contra…