Cancer Variant Interpretation for Precision Oncology Comprehensive clinical interpretation of somatic mutations in cancer. Transforms a gene + variant input into an actionable precision oncology report covering clinical evidence, therapeutic options, resistance mechanisms, clinical trials, and prognostic implications. KEY PRINCIPLES : 1. Report-first approach - Create report file FIRST, then populate progressively 2. Evidence-graded - Every recommendation has an evidence tier (T1-T4) 3. Actionable output - Prioritized treatment options, not data dumps 4. Clinical focus - Answer "what should w…