Drug Target Validation Pipeline Validate drug target hypotheses using multi-dimensional computational evidence before committing to wet-lab work. Produces a quantitative Target Validation Score (0-100) with priority tier classification and GO/NO-GO recommendation. Reasoning Before Searching A valid drug target must pass 4 gates in order. Failing an early gate makes later gates irrelevant: 1. Genetic evidence linking it to disease : Does human genetic data (GWAS, rare variant studies, Mendelian genetics) support this target's role? Genetic evidence is the strongest predictor of clinical succes…