Immunotherapy Response Prediction Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Transforms a patient tumor profile (cancer type + mutations + biomarkers) into a quantitative ICI Response Score with drug-specific recommendations, resistance risk assessment, and monitoring plan. Reasoning Before Searching Not all tumors respond to checkpoint inhibitors. Reason through the biology before running tools: - TMB (tumor mutational burden) : More somatic mutations produce more neoantigens, which are recognized by T cells. High TMB ( =10 mut/Mb, FDA-…