Small Molecule Discovery Skill Systematic small molecule identification, characterization, and sourcing using PubChem, ChEMBL, BindingDB, ADMET-AI, SwissADME, eMolecules, and Enamine. Covers the full pipeline from compound name to structure, activity, ADMET properties, and commercial procurement. Domain Reasoning Drug-likeness is not a binary property. Lipinski's Rule of 5 was derived from orally administered, passively absorbed drugs and has many well-known exceptions: natural products, macrocycles, PROTACs, and many approved drugs violate one or more rules. The relevant question is not "doe…